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Workforce Training

Biotechnology Certifications

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Virtual Tour   

Wake Tech offers short, non-degree classes and certificate programs in biotechnology. Students get hands-on experience in biomanufacturing and biopharmaceutical operations in a simulated industrial setting that follows current Good Manufacturing Practices (cGMP). This training prepares students for jobs in the biotech industry by focusing on real-world skills and industry standards.

Interested in earning a degree to work in the biotech industry? Visit Wake Tech's Biotechnologies Division.

BioWork Process Technician

Biotechnology Career Field Courses

BioWork: Process Technician Training

  • Course ID: BTC-3200A7
  • Overview
  • Course Outline
  • Requirements
  • Intended Audience
  • More Details
The BioWork Process Technician course is designed to provide basic preparation for entry-level process technician jobs in bioprocess manufacturing, pharmaceutical manufacturing and chemical manufacturing. BioWork provides competencies to include understanding the role of a process technician, safety, quality processes, measuring process variables, transforming matter, process technology (including processing equipment and plant utilities), controlling the process, maintaining sterile processes and growing living cells. BioWork graduates are sought after to become employed in the biopharmaceutical industry in Wake County and surrounding counties. BioWork certification feeds into two Wake-Tech degree programs, which means a BioWork graduate can pursue an associate degree at Wake Tech after being hired in the industry. Many industries in the area provide educational benefit for their employees. What that means for the BioWork graduate is a job and the potential to earn a degree with very little out-of-pocket costs, which equals not only employment opportunities but also opportunities for advancement. BioWork is also a Propel Scholarship-sponsored program at Wake Tech, which means you can potentially earn this certification for little cost.

Course Objectives

Demonstrate knowledge and competence in the academic and technical fields related to bioprocess manufacturing

Use critical thinking to analyze and solve problems

Communicate effectively

Demonstrate positive, effective and appropriate interpersonal skills


Outline of Instruction

Unit 1: Pharmaceutical Quality and CGMP - Quality methods, standards and practices utilized in the biomanufacturing industry and how the federal government regulates and enforces them.

Unit 2: Working Safely - Hazards and risks within the biomanufacturing industry and how industry practices, education and federal agencies such as OSHA work to minimize these hazards and risks

Unit 3: Measuring Process Parameters - Process variables such as length, mass, volume, pressure and other parameters are measured and converted back and forth between the metric and English unit systems

Unit 4: Chemical Processes in Biomanufacturing - Introduction to common chemicals in the workplace, basic chemical safety, nature of chemicals, chemical families, chemical reactions and mixtures/solutions

Unit 5: Equipment and Utilities - Discussion of inputs, process steps, outputs, facility organization, process equipment (tanks, piping systems, pumps, valves and seals), facility utilities (gases, water, steam, heating and cooling, hydraulics, electricity and waste treatment)

Unit 6: Controlling the Process - Common unit operations, separation methods and equipment, process control parameters and methods, process control instrumentation and manual/automatic control methods

Unit 7: Facilities and the Manufacturing Environment - Facility design and operation considerations including biopharmaceutical facility regulatory requirements, facility monitoring and maintenance and contamination control concerns/methods

Unit 8: Biomanufacturing Production - Detailed discussion of biomanufacturing steps that are common to many product types and specific production steps unique to or found in a number of special product categories

In addition to the above-mentioned unit materials contained within the BioWork textbook, instruction and discussion about job-seeking skills such as resume development, searching for jobs online, LinkedIn or other professional networking tools and interview questions is included in this course. Students are strongly encouraged and invited to attend virtual career fairs that as many as 30 industry partners attend.


Contact Hours

150

CEUs

Yes

Industry Standard, State or National Certification

Certification

Partnership for Biotechnology Workforce Training - Process Technician Examination

Website

https://www.scantron.com/wp-content/uploads/2019/07/NCBC-Candidate-Guid…

Certification Learning Outcomes/Requirements

Complying with cGMP (current Good Manufacturing Practices)

Following an SOP (Standard Operating Procedure)

Completing Batch Records

Reading an SDS (Safety Data Sheet)

An awareness of the importance of safety for the workers and product

Using the metric system and measuring process parameters

Understanding mechanical components of process operations (tanks, pumps, valves, etc.)

Reading gauges

Understanding different utility requirements (water, air, electrical, waste systems) for different parts of process operations

Reading process diagrams and understanding feedback systems

Determining manufacturing process similarities and differences for various product types

Resume writing, job interview and networking skills


CE or CU Articulation

Bioprocess Practices, BPM-110, and Industrial Environment, PTC-110

Prerequisites

Students who wish to register for BioWork must possess a high school diploma or GED and must complete an online information session.

Learning Supplies Needed

"BioWork: An Introductory Course for Process Technicians, Third Edition," Revised 2020

Clinical Site/Special Facilities

Lab module or virtual replacements for onsite laboratory exercises

Requirements for Successful Completion

80% attendance
Students must score an 80% on each unit exam to stay in the course. Students are allowed one retest of each unit exam to reach that 80% score.,An approved resume from N.C. BioNetwork or Biotechnology Career Navigator

Accreditation/Special Approval Requirements

High school diploma or General Education Diploma

Intended Audience

Those with at least a high school diploma or GED who are unemployed, transitioning, especially from other manufacturing sectors, or starting a new career. This course can also be useful for individuals with degrees in biological sciences, chemistry, biochemistry or other fields who want to enter employment in biomanufacturing or pharmaceutical manufacturing and lack the knowledge of the products, regulations and manufacturing methods used in these industries.

Specific Industry or Business Support Needs

Bioprocess Technician 3 or 4, Manufacturing Process Technician I, Operation Specialist

Wake County Need for Industry Positions

Many employers within Wake County and surrounding counties

Industry or Job Titles Related to Training Outcomes for Employment

Manufacturing process technician

Bioprocess technician

Operation specialist

Related Courses

Course Contact Information

Siobhan D'Antonio

[email protected]

Current Opportunities
Details Section Date(s) Location Price Seats  
329573 06/02/26 - 07/28/26 Eastern Wake Campus 243.00 6 Register
329765 06/15/26 - 08/12/26 RTP Campus 243.00 10 Register
329781 06/16/26 - 08/13/26 Western Wake Campus 243.00 5 Register
330035 06/23/26 - 08/11/26 Southern Wake Campus 243.00 11 Register

If you would like to be notified when additional sections become available, please use Wake Tech’s Notify Me service for BTC-3200A7-BioWork: Process Technician Training .

Micropipetting Techniques for Precision & Accuracy

  • Course ID: SEF-79654
  • Overview
  • Course Outline
  • Requirements
  • Intended Audience
  • More Details
Micropipettes are common laboratory devices used to accurately dispense small volumes of liquid samples. This course focuses on the principles of micropipetting used in biotechnology and other laboratory settings. Testing of pipetting skills will be made at the entry of the class and at the end of the course to access the student’s improvement. Practical tips and techniques are discussed and practiced to increase accuracy and precision of pipetting. Ergonomics is discussed as it relates to the prevention of injuries due to repetitive motions in laboratory situations, with particular emphasis on pipetting activities.

Course Objectives

Introduce the basic skills of micropipette operation

Provide experience with a variety of micropipettes commonly encountered in laboratory situations

Discuss and practice techniques used to increase pipetting performance

Provide students with a means to quantify their pipetting skills and measure gains in those skills acquired during the course

Provide an introduction to the dilution of laboratory reagents/samples and the calculations needed to make those dilutions

Introduce the topic of ergonomics as it applies to laboratory procedures and the prevention of workplace injuries


Outline of Instruction

Lecture: The use and function of micropipettes

Lab: Initial micropipetting skill level testing (Artel method)

Lecture: Factors affecting pipetting performance

Lecture: Methods to quantify micropipette performance

Lecture: Guide to dilutions

Lab: Pipetting

Lecture: Tips for better pipetting

Lecture: Ergonomics and micropipetting

Lab: Pipetting and the gravimetric method of measuring pipetting performance

Lab: Practice pipetting with glass, serological and digital pipettes

Lab: Final test of pipetting performance (Artel method)

Open floor for additional questions and feedback


Contact Hours

7

CEUs

Yes

Industry Standard, State or National Certification

Certification

None

Website

None

Certification Learning Outcomes/Requirements

CE or CU Articulation

No

Prerequisites

Minimum of a high school diploma/GED or relevant industry work experience. Some exposure to pipetting techniques is beneficial, but is not required.

Learning Supplies Needed

Study materials, including copies of lecture slides, additional reference material and laboratory exercises, will be provided by the instructor.

Clinical Site/Special Facilities

N/A

Requirements for Successful Completion

95% attendance
Coefficient of variation (CV) < 1% with micropipettes in two attempts or fewer

Accreditation/Special Approval Requirements

N/A

Intended Audience

Specific Industry or Business Support Needs

N/A

Wake County Need for Industry Positions

N/A

Industry or Job Titles Related to Training Outcomes for Employment

Related Courses

Course Contact Information

Siobhan D'Antonio

[email protected]

No active courses available at this time.

To be notified when this course becomes available, please use Wake Tech’s Notify Me service for SEF-79654-Micropipetting Techniques for Precision & Accuracy .

Writing Effective SOPs

  • Course ID: SEF-3001ME1
  • Overview
  • Course Outline
  • Requirements
  • Intended Audience
  • More Details
Students learn how to write an effective Standard Operating Procedure (SOP) as well as why these are a required and essential component of documentation systems in regulated industries. Discussion includes the functional areas in which SOPs are needed, the qualities that make them effective and the importance of keeping these current. Students learn how to structure an SOP and the content that should be included. Hands-on activities include reviewing and critiquing an SOP for completeness and effectiveness, as well as practice writing SOPs.

Course Objectives

Explain the regulatory and business rationale for SOPs

Identify FDA expectations

Define at least two approaches for determining what SOPs are needed

Identify factors that support SOP efficacy

Distinguish between methods of presenting SOP content

Analyze the structure and content of an SOP for adherence to the principles of effective SOP construction

Create an SOP utilizing the principles learned in class

Understand how to keep SOPs current


Outline of Instruction

Principles, philosophy, regulatory compliance

Overview and analysis of SOP examples for effectiveness

Create an SOP (or virtual SOP for online classes) per the principles discussed in class


Contact Hours

4

CEUs

No

Industry Standard, State or National Certification

Certification

None

Website

None

Certification Learning Outcomes/Requirements

CE or CU Articulation

No

Prerequisites

N/A

Learning Supplies Needed

Provided with course delivery

Clinical Site/Special Facilities

Classroom with projection capability

Requirements for Successful Completion

95% attendance

Accreditation/Special Approval Requirements

N/A

Intended Audience

Biomanufacturing, bioprocessing, pharmaceutical, medical device, cosmetics and other FDA-regulated industry sectors

Specific Industry or Business Support Needs

Quality, Manufacturing, Management

Wake County Need for Industry Positions

N/A

Industry or Job Titles Related to Training Outcomes for Employment

Quality

Manufacturing

Management

Related Courses

Course Contact Information

BioNetwork Manager

[email protected]

No active courses available at this time.

To be notified when this course becomes available, please use Wake Tech’s Notify Me service for SEF-3001ME1-Writing Effective SOPs .

FDA Audit Preparation

  • Course ID: SEF-3001MC1
  • Overview
  • Course Outline
  • Requirements
  • Intended Audience
  • More Details
This course is designed to help create an environment of preparedness and a culture of quality assurance by raising the awareness of FDA compliance in regulated facilities. Maintaining current knowledge of preparation steps, do's and don'ts, documentation completeness and thoroughness and an understanding of real-time preparedness can help to reduce employee stress during an actual audit. This course equips professionals who will experience FDA audits to maintain compliance by following and documenting in accordance with cGMP.

Course Objectives

Attain an understanding of the importance of both internal and external audits

Describe the relationship between FDA auditing activities and cGMP compliance through the Code of Federal Regulations (CFR) for pharmaceuticals

Identify audit findings from real company inspections

Explain do's and don'ts for FDA audits

Distinguish the roles of company representatives during an audit

Relate the importance of proper documentation to provide evidence of compliance with cGMP

Perform an audit of a document used in the biopharmaceutical industry


Outline of Instruction

Reasons for and the importance of audits

What is fair game during an audit

Preparing for an audit

Do's and don'ts

Company responsibilities

Preparation activities and documentation

Review of 483s and warning letters

Things to know about an FDA audit

What to expect

Auditor roles and rights

Auditor responsibilities

Review of sample documentation


Contact Hours

4

CEUs

No

Industry Standard, State or National Certification

Certification

None

Website

None

Certification Learning Outcomes/Requirements

CE or CU Articulation

No

Prerequisites

N/A

Learning Supplies Needed

Provided by BioNetwork

Clinical Site/Special Facilities

N/A

Requirements for Successful Completion

100% attendance

Accreditation/Special Approval Requirements

N/A

Intended Audience

Team leaders and supervisors, regulatory personnel, quality control personnel, quality assurance personnel, manufacturing technicians, administrative personnel (scribes), maintenance/engineers

Specific Industry or Business Support Needs

N/A

Wake County Need for Industry Positions

N/A

Industry or Job Titles Related to Training Outcomes for Employment

Team leaders and supervisors

Regulatory personnel

Quality control personnel

Quality assurance personnel

Manufacturing technicians

Administrative personnel (scribes)

Maintenance/engineers

Related Courses

SEF-79524

SEF-414CL

SEF-211CL


Course Contact Information

BioNetwork Manager

[email protected]

No active courses available at this time.

To be notified when this course becomes available, please use Wake Tech’s Notify Me service for SEF-3001MC1-FDA Audit Preparation .

Advanced Technical Writing

  • Course ID: SEF-3001MG1
  • Overview
  • Course Outline
  • Requirements
  • Intended Audience
  • More Details
Technical writing is an important part of the life science industry, but only if the reader understands what it is they are reading. Participants learn some or the more advanced techniques and tools that help them better organize, write and edit scientific documents, including regulatory documents, manuscripts, grant proposals, posters, presentations, SOPs, protocols, reports (internal or external), articles and papers. Topics covered include 30 rules for effective technical writing, 10 guidelines to make you a better technical writer and numerous examples and exercises to demonstrate effective technical writing, all from a scientific perspective, so each participant can immediately become a better writer.

Course Objectives

Learn the 30 basic rules for technical writing and apply these to scientific examples

Learn the 10 basic guidelines for technical writing that support the technical writing rules and apply these to scientific examples

Complete writing examples/exercises that support the rules and guidelines to become a better writer

Evaluate a sample document for compliance with the rules and guidelines discussed in the class


Outline of Instruction

Organizing writing for SOPs, protocols, internal or external reports, manuscripts, grant proposals, posters, presentations, job applications letters, articles and papers

Understanding readers (your audience) to facilitate better communication

Review of the 30 rules for effective technical writing with examples

Review of the 10 guidelines that assist in achieving effective technical writing, with examples

Topics that enhance your style of writing

How to compose to match your writing style

Recognizing the topic and stress positions in sentences

Recognizing the topic and stress positions in paragraphs

Taking sentences to paragraphs

Planning and laying the foundation for technical writing


Contact Hours

6

CEUs

No

Industry Standard, State or National Certification

Certification

None

Website

None

Certification Learning Outcomes/Requirements

CE or CU Articulation

No

Prerequisites

N/A

Learning Supplies Needed

N/A

Clinical Site/Special Facilities

N/A

Requirements for Successful Completion

80% attendance

Accreditation/Special Approval Requirements

N/A

Intended Audience

Pharmaceutical, biomanufacturing, cosmetics, biotechnology positions for quality control, quality assurance, regulatory, engineering, laboratory, manufacturing or any other associate that is required to write their observations or findings for readers to understand

Specific Industry or Business Support Needs

N/A

Wake County Need for Industry Positions

N/A

Industry or Job Titles Related to Training Outcomes for Employment

Related Courses

SEF-3001MA1


Course Contact Information

Siobhan D'Antonio

[email protected]

No active courses available at this time.

To be notified when this course becomes available, please use Wake Tech’s Notify Me service for SEF-3001MG1-Advanced Technical Writing .

Upstream Processing

  • Course ID: SEF-3001MF1
  • Overview
  • Course Outline
  • Requirements
  • Intended Audience
  • More Details
Upstream processing is the initial phase of the bioprocess from cell line development and cultivation to culture expansion of the cells through bioproduct harvesting. In this course, students learn techniques such as subculturing (cell passaging), cell growth monitoring and contamination mitigation. Students also have hands-on experience performing cell counts, extracting media samples from a bioreactor and analyzing cell samples using a bio-analyzer to determine the growth rate of the cells.

Course Objectives

Compare and contrast key differences between microbial fermentation and cell culture in terms of equipment, cell growth, biological products, support systems, nutrients and sterility assurance

Identify components of a pilot-scale fermenter (BioFlo 320), practice monitoring the exponential growth of E.coli by tracking growth parameters such as pH and dissolved oxygen (DO), develop an E.coli growth curve in a batch production record (BPR) using optical density (OD) measurements from a UV/Vis spectrophotometer

Demonstrate the importance of sterility assurance with hands-on activities with both contaminated and healthy cell lines, apply the fundamentals of aseptic technique through Chinese hamster ovary (CHO) cell subculturing (cell passage) inside a biological safety cabinet (BSC)

Monitor cell viability, metabolite quality and osmotic conditions of mammalian cell growth using a cell counter, bioanalyzer and osmometer; observe the impact of cell growth parameters such as pH and oxygen on cell culture maintenance with a blood gas analyzer

Engage with upstream processing single-use technologies such as mixers, containers and tubing; prepare aseptic tubing using a tube welder, single-use tube connectors and sterile filters


Outline of Instruction

Introduction: Fundamentals of upstream processing, fermentation lab (Part I), upstream facilities, equipment and control, tools of the trade, fermentation lab (Part II)

Cell Culture: Cell culture lecture, working with mammalian cells, analyte testing, analyte and metabolite testing lab, single-use technology, aseptic connection demonstration and course wrap-up


Contact Hours

16

CEUs

No

Industry Standard, State or National Certification

Certification

None

Website

None

Certification Learning Outcomes/Requirements

CE or CU Articulation

No

Prerequisites

N/A

Learning Supplies Needed

N/A

Clinical Site/Special Facilities

N/A

Requirements for Successful Completion

80% attendance

Accreditation/Special Approval Requirements

N/A

Intended Audience

Bioprocess technicians, bioprocess engineers, manufacturing associates, fermentation technicians, fermentation lab analysts

Specific Industry or Business Support Needs

N/A

Wake County Need for Industry Positions

N/A

Industry or Job Titles Related to Training Outcomes for Employment

Bioprocess technicians, bioprocess engineers, manufacturing associates, fermentation technicians, fermentation lab analysts

Related Courses

Course Contact Information

Siobhan D'Antonio

[email protected]

No active courses available at this time.

To be notified when this course becomes available, please use Wake Tech’s Notify Me service for SEF-3001MF1-Upstream Processing .

Downstream Processing

  • Course ID: SEF-3001MD1
  • Overview
  • Course Outline
  • Requirements
  • Intended Audience
  • More Details
Biopharmaceutical processes are used in upstream processing to create materials that can be purified in downstream processes to produce the desired drug product, including antibiotics, hormones, amino acids or therapeutic proteins. Through a mixture of lecture and hands-on activities, students learn the fundamentals of downstream processing (DSP) that are essential to the purification of these products. Topics include equipment, harvesting, solid-liquid separation, filtration, purification, chromatography, column packing, bulk fill and production yields.

Course Objectives

Recall fundamental topics of downstream processing and define individual steps, such as cell disruption, solid-liquid separation and purification through daily content refreshers and assessments

Explain key differences between filtration, viral clearance and diafiltration. Practice the purification and concentration of proteins through hands-on filtration and diafiltration activities using a batch production record (BPR).

Define the purpose of chromatography and identify different types of chromatography, including ion-exchange chromatography and hydrophobic interaction chromatography. Explain basic protein chemistry and the importance of absorbance for total protein identification.

Identify the importance of column packing and distinguish factors that impact column packing, such as mobile phase and resin selection. Practice column packing calculations and observe a column packing demonstration.

Identify the component of a small-scale chromatography system (ÄKTA Start). Conduct an anion-exchange chromatography (AEX) run through the preparation and A395 analysis of green fluorescent protein (GFP) using the ÄKTA Start Chromatography Systems. Calculate GFP production yield and column performance, such as height equivalent to a theoretical plate (HETP) and asymmetry.


Outline of Instruction

Introduction: Downstream processing overview, filter integrity test, tangential flow filtration (TFF), ÄKTA start ID/filtrate preparation/setup, chemistry review and wrap-up

Chromatography Day: Chromatography operations, column packing, column packing demo, AEX run, single use in DSP and wrap-up


Contact Hours

16

CEUs

No

Industry Standard, State or National Certification

Certification

None

Website

None

Certification Learning Outcomes/Requirements

CE or CU Articulation

No

Prerequisites

N/A

Learning Supplies Needed

N/A

Clinical Site/Special Facilities

N/A

Requirements for Successful Completion

90% attendance

Accreditation/Special Approval Requirements

N/A

Intended Audience

Bioprocess technicians, bioprocess engineers, manufacturing associates, fermentation technicians, fermentation lab analysts

Specific Industry or Business Support Needs

N/A

Wake County Need for Industry Positions

N/A

Industry or Job Titles Related to Training Outcomes for Employment

Bioprocess technicians, bioprocess engineers, manufacturing associates, fermentation technicians, fermentation lab analysts

Related Courses

Course Contact Information

Siobhan D'Antonio

[email protected]

No active courses available at this time.

To be notified when this course becomes available, please use Wake Tech’s Notify Me service for SEF-3001MD1-Downstream Processing .

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