BioNetwork Training

The BioNetwork Capstone Center provides affordable, high-quality, hands-on training in biotechnology, biomanufacturing, and biopharmaceutical/pharmaceutical operations in a simulated industrial (cGMP) environment.

The Capstone Center is situated in the Golden LEAF Biomanufacturing Training and Education Center (BTEC) at North Carolina State University Centennial Campus. It provides a training environment that mirrors a biomanufacturing plant facility with state-of-the-art classrooms, industrial-grade equipment laboratories, and a certified cleanroom suite.

Industry-recognized credential: BioNetwork Capstone Certificates

Complete in: 12 months or less

For non-credit student support services or to see if you qualify for financial assistance, contact the Career Pathways Program & Student Resources. 

Get Support


Course Details & Registration Information

Fermentation Processes
Available Classes
Not currently offered.
Description Course Outline Requirements Intended Audience More Details
Learn the fundamentals of fermentation technology and processes in the chemical and biotechnology industries. Lecture topics include microbial nutrition and growth, sterilization principles, fermentation equipment/instrumentation, operations, and regulatory considerations. Labs provide hands-on experience with shaker and bioreactor production, media preparation, and use of analytical lab equipment.
Course Objectives
  1. Explore the fundamentals of fermentation including: the history of fermentation, industrial microorganisms and products, cGMP considerations in fermentation, microbial nutrition and growth, cell metabolism and product formation, sterilization, fermentor design, instrumentation and control, and fermentation support systems and operations.
  2. Gain hands-on experience in: sterilization, media preparation, and culture operations at both the shaker flask and bioreactor scale.
Outline of Instruction
  1. Day 1 Lectures
    a. Introduction to fermentation processes (history)
    b. Industrial microorganisms and their products
    c. Current good manufacturing practices as directed to fermentation processes
    d. Sterilization Rules
    e. Nutrition and Cell Growth
    f. Metabolism and Product Improvement
  2. Day 1 Labs
    a. Review lab safety
    b. Refresh a culture
    c. Prepare shaker flask media
    d. Microscope observations
  3. Day 2 Lectures
    a. Fermentor Design
    b. Fermentation Instrument and Control
    c. Fermentation Support Systems
    d. Fermentation Operations
  4. Day 2 Labs
    a. Inoculate and monitor shaker flasks for growth
    b. Identify nutrition components of various media
    c. Perform a sterilization investigation
  5. Day 3 Lecture - Single Use Technologies
  6. Day 3 Labs
    a. Identify parts of bioreactor
    b. Inoculate bioreactor and monitor throughout day
    c. Use of additional analytical equipment for monitoring
    d. Clean-up and store
Contact Hours
Industry Standard, State, or National Certification
CE to CU Articulation
Text and Supplies Needed
Clinical Site/Special Facilities
Classroom and teaching laboratory
Requirements for Successful Completion of this Course
  1. Attendance 95% or above
  2. Participation
Accreditation/Special Approval Requirements
Intended Audience
Specific Industry or Business Support Needs
Industry or Job Titles Related to training Outcomes for Employment
Related Courses
Course Contact Information
Bionetwork Manager